The use of placebos in clinical trials: responsible research or unethical practice?
نویسنده
چکیده
منابع مشابه
A duty to deceive: placebos in clinical practice.
Among medical researchers and clinicians the dominant view is that it is unethical to deceive patients by prescribing a placebo. This opinion is formalized in a recent policy issued by the American Medical Association (AMA [Chicago, IL]). Although placebos can be shown to be always safe, often effective, and sometimes necessary, doctors are now effectively prohibited from using them in clinical...
متن کاملIs It Always Unethical to Use a Placebo in a Clinical Trial?
BACKGROUND TO THE DEBATE Placebos are used in trials to conceal whether a treatment is being given or not and hence to control for the psychosomatic effects of offering treatment. Placebo-controlled trials are controversial. Critics of such trials argue that if a proven effective therapy exists, a placebo should not be used. But proponents argue that placebo trials are still crucial to prove th...
متن کاملThe Use of Placebo and the Right of Autonomy
In the clinical trial context, given that placebo-controlled trials do not subject participants to serious or irreversible harm, placebo use is ethically justified because the participation is autonomous. In the clinical practice context, assuming that the open use of placebos is ineffective, placebos can be used deceptively without violating patients’ right of autonomy and therefore can also b...
متن کاملEthics in the design and conduct of clinical trials.
Received for publication August 21, 2001, and accepted for publication February 12, 2002. 1 Center for the Study of Medical Ethics and Humanities, Duke University, Durham, NC. 2 Departments of Medicine and Philosophy, Duke University, Durham, NC. Correspondence to Dr. Jeremy Sugarman, 108 Seeley G. Mudd Building, Duke University Medical Center (Box 3040), Durham, NC 27710 (e-mail: [email protected]...
متن کاملBiological, clinical, and ethical advances of placebo effects.
For many years, placebos have been defined by their inert content and their use as controls in clinical trials and treatments in clinical practice. Recent research shows that placebo effects are genuine psychobiological events attributable to the overall therapeutic context, and that these effects can be robust in both laboratory and clinical settings. There is also evidence that placebo effect...
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عنوان ژورنال:
- Connecticut law review
دوره 33 2 شماره
صفحات -
تاریخ انتشار 2001